Effect of Pramiracetam on Memory Post ABI

Author/Year/
Country/Study design/PEDro Score

Methods

Outcomes

McLean Jr. et al. (1991)
USA
RCT
PEDro=5
N=4

 

Population: TBI; Age Range=23-37yr; Gender: Male=4, Female=0.
Treatment: Patients were treated in two, 3wk blocks of oral pramiracetam (400mg, 2x/d) and placebo over 12wk.  Outcome Measure:  Wechsler Memory Scale (WMS), Selective Reminding Test, Trail Making Test A&B, Finger Tapping Test, Digit Symbol Test, Word Fluency Test.

  1. Improvements in immediate and delayed recall in the WMS (logical memory and selecting reminding test) were found for the treatment group.

 

 

*statistical values not provided in the study

PEDro = Physiotherapy Evidence Database rating scale score (Moseleyet al. 2002).