Nursal et al. (2007)
Population: TBI; Control Group (n=9): Mean Age=43yr; Gender: Male=8, Female=1; Mean GCS Score=8.9. Treatment Group (n=10): Mean Age=43.8yr; Gender: Male=8, Female=2; Mean GCS Score=7.7.
Treatment: Patients in the treatment group were administered 10mg (2 mL) IV metoclopramide 3×/d for 5d. The control group received the same volume of control saline solution for the same duration.
Outcome Measure: Paracetamol absorption test, amount of calories supplied, intolerance and/or complication rates.
- Amount of oral/enteral calories in relation to the total number of calories received during the first 5 d was higher for those in the control group (p=0.043).
- There were no differences between the groups in both feeding intolerance and complications rates (p=0.543 and p=0.930, respectively).
- There was no significant difference between the groups when looking at the results of the paracetamol absorption test.
- When looking at absorption parameters, those in the treatment group had levels that were slightly more pronounced than those in the control group.